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P10493

Nidogen-1 (P10493)

Uniprot ID P10493
Protein Name Nidogen-1
Gene Name Nid1
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.669
Function Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions.
GO - Molecular function
  • calcium ion binding : IEA:InterPro
  • collagen binding : IDA:MGI
  • extracellular matrix binding : IDA:MGI
  • laminin binding : ISO:MGI
  • laminin-1 binding : IDA:MGI
  • proteoglycan binding : ISO:MGI
GO - Biological process
  • cell-matrix adhesion : IDA:MGI
  • extracellular matrix organization : IDA:MGI
  • glomerular basement membrane development : IMP:MGI
  • positive regulation of cell-substrate adhesion : IDA:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.